This one‑day meeting will showcase cutting‑edge advances in complex cellular systems, animal‑replacement technologies, and new approach methodologies (NAMs) that are reshaping translational research and reducing reliance on traditional in vivo models. As regulatory expectations evolve and the scientific community accelerates toward human‑relevant, mechanism‑driven discovery, the event offers a timely forum for delegates to explore emerging technologies that deliver greater physiological relevance, improved predictivity, and enhanced ethical sustainability. Through expert talks, interactive discussions, and technology demonstrations, attendees will gain a clear understanding of how these next‑generation models, including organoids, microphysiological systems, and co‑culture platforms, can be integrated into discovery pipelines today.

Delegates will leave with three key learnings:

1. A critical view of the latest complex cellular, NAM, and animal‑replacement systems and their translational value.
2. Practical strategies for replacing or reducing animal models while maintaining scientific robustness.
3. Actionable insights on implementation, including assay design, validation considerations, and operational challenges.